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Leonard H Augenlicht Selected Research

Cyclin-Dependent Kinase Inhibitor p21

10/2005p27kip1 in intestinal tumorigenesis and chemoprevention in the mouse.
4/2005Inactivation of p21WAF1/cip1 enhances intestinal tumor formation in Muc2-/- mice.
12/2002Short chain fatty acids and colon cancer.
8/2002Environment-gene interactions in intestinal cancer.

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Leonard H Augenlicht Research Topics

Disease

34Neoplasms (Cancer)
01/2021 - 08/2002
21Colonic Neoplasms (Colon Cancer)
01/2020 - 11/2002
14Colorectal Neoplasms (Colorectal Cancer)
01/2021 - 12/2003
10Carcinogenesis
01/2020 - 08/2002
5Carcinoma (Carcinomatosis)
10/2010 - 01/2002
4Adenomatous Polyposis Coli (Familial Adenomatous Polyposis)
01/2021 - 01/2002
3Inflammation (Inflammations)
05/2016 - 05/2012
3Intestinal Neoplasms (Intestinal Cancer)
11/2011 - 05/2009
3Adenoma (Adenomas)
11/2011 - 08/2003
2Lung Neoplasms (Lung Cancer)
01/2013 - 03/2008
2Adenocarcinoma
11/2011 - 10/2010
2Breast Neoplasms (Breast Cancer)
03/2008 - 09/2004
2Ovarian Neoplasms (Ovarian Cancer)
05/2007 - 04/2004
1Weight Gain
05/2012
1Microsatellite Instability
10/2009
1Neoplasm Metastasis (Metastasis)
07/2008

Drug/Important Bio-Agent (IBA)

7CalciumIBA
01/2020 - 08/2003
7Proteins (Proteins, Gene)FDA Link
01/2013 - 03/2005
7beta CateninIBA
05/2009 - 01/2002
6Pharmaceutical PreparationsIBA
07/2008 - 04/2003
6Sulindac (Copal)FDA LinkGeneric
03/2008 - 12/2002
5Vitamin DFDA LinkGeneric
01/2020 - 08/2003
5Butyrates (Butyrate)IBA
09/2014 - 01/2002
5Small Interfering RNA (siRNA)IBA
01/2011 - 05/2007
5Cyclin D1IBA
10/2010 - 09/2004
4Cholecalciferol (Vitamin D3)FDA Link
01/2020 - 03/2009
4Histone Deacetylase InhibitorsIBA
06/2015 - 05/2007
4Volatile Fatty AcidsIBA
10/2010 - 01/2002
4Cyclin-Dependent Kinase Inhibitor p21IBA
10/2005 - 08/2002
3Differentiation AntigensIBA
06/2015 - 11/2008
3Butyric Acid (Butanoic Acid)IBA
09/2014 - 01/2002
3CytokinesIBA
01/2014 - 08/2003
3Biological ProductsIBA
09/2010 - 04/2004
2Dietary CalciumIBA
05/2016 - 01/2009
2Kruppel-Like Transcription Factors (Kruppel-Like Factors)IBA
06/2015 - 09/2014
2Alkaline PhosphataseIBA
06/2015 - 09/2014
2Biomarkers (Surrogate Marker)IBA
01/2010 - 03/2008
2ErbB Receptors (EGF Receptor)IBA
10/2009 - 03/2008
2Messenger RNA (mRNA)IBA
10/2009 - 03/2005
2IsoenzymesIBA
05/2009 - 05/2007
2Complementary DNA (cDNA)IBA
11/2008 - 12/2003
2Fluorouracil (Carac)FDA LinkGeneric
07/2008 - 12/2003
2Histone Deacetylases (Histone Deacetylase)IBA
05/2007 - 05/2006
2CarcinogensIBA
11/2003 - 08/2003
1Pemetrexed (MTA)FDA Link
01/2021
15'-methylthioadenosine phosphorylase (methylthioadenosine nucleosidase)IBA
01/2021
1TamoxifenFDA LinkGeneric
01/2020
1Complement System Proteins (Complement)IBA
01/2017
1Calcitriol (Calcijex)FDA LinkGeneric
05/2016
1EnzymesIBA
09/2014
1Cytokine Receptor gp130IBA
01/2014
1Cytokine Receptors (Cytokine Receptor)IBA
01/2014
1Estrogens (Estrogen)FDA Link
01/2014
1Insulin (Novolin)FDA Link
01/2014
1Interleukin-1 (Interleukin 1)IBA
01/2014
1InterleukinsIBA
01/2014
1LeptinIBA
01/2014
1Interleukin-6 (Interleukin 6)IBA
01/2014
1AntigensIBA
10/2013
1Phenobarbital (Luminal)FDA Link
10/2013
1Interleukin-8 (Interleukin 8)IBA
01/2013
1Fatty Acids (Saturated Fatty Acids)IBA
05/2012
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
11/2011
1CateninsIBA
11/2011
1Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA
11/2011
1Phosphoric Monoester Hydrolases (Phosphatases)IBA
11/2011
1TensinsIBA
11/2011
1Mucin-1 (CA 15-3 Antigen)IBA
01/2011
1Oncogene Proteins (Oncogene Protein)IBA
01/2011
1NucleotidesIBA
10/2010
1Oxaliplatin (Eloxatin)FDA LinkGeneric
07/2010
1ParaffinIBA
01/2010
1Formaldehyde (Formol)FDA Link
01/2010
1Adenosine (Adenocard)FDA LinkGeneric
10/2009
11,25-dihydroxyvitamin DIBA
03/2009
1Dietary FiberFDA Link
01/2009
1Folic Acid (Vitamin M)FDA LinkGeneric
01/2009
1Choline (Choline Chloride)IBA
01/2009
1Methionine (L-Methionine)FDA Link
01/2009
1LipidsIBA
01/2009
1Selenium-Binding ProteinsIBA
11/2008
1Proliferating Cell Nuclear Antigen (PCNA)IBA
11/2008
1Carcinoembryonic AntigenIBA
11/2008
1DecorinIBA
07/2008
1Trefoil Factor-3IBA
07/2008
1Cadherins (E-Cadherin)IBA
07/2008
1Small Leucine-Rich ProteoglycansIBA
07/2008
1Cetuximab (Erbitux)FDA Link
03/2008
1Cyclin-Dependent Kinases (cdk Proteins)IBA
07/2007
1Phosphotransferases (Kinase)IBA
07/2007
1romidepsin (FK228)FDA Link
05/2007
1Protein Isoforms (Isoforms)IBA
05/2007
1histone deacetylase 3IBA
05/2006
1Indicators and Reagents (Reagents)IBA
05/2006
1Niacin (Nicotinic Acid)FDA LinkGeneric
05/2006

Therapy/Procedure

4Therapeutics
01/2010 - 12/2003
3Drug Therapy (Chemotherapy)
07/2008 - 06/2004
2Chemoprevention
10/2005 - 11/2002
1Colectomy
01/2021
1Caloric Restriction
03/2013